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Previous studies pointed that astrocytic α-synuclein deposition initiates the recruitment of phagocyte microglia that attacks and kills neurons in restricted brain regions [7,19], correlating this α-synuclein accumulation with nigral neuronal cell death [20], and suggest the importance of astrocytes in the initiation of the disease

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Research indicates that individuals with ASD have higher MDA concentrations in their urine and blood, suggesting increased oxidative stress and lipid peroxidation throughout their bodies [28,29]